Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 6/20 | 0.34 |
| ▸ | JAK1 | P23458 | 6/20 | 0.34 |
| ▸ | TYK2 | P29597 | 6/20 | 0.34 |
| ▸ | JAK3 | P52333 | 6/20 | 0.34 |
| ▸ | EP300 | Q09472 | 6/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | BCDIN3D | Q7Z5W3 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29498913 | 0.93 | JAK2 (0.35) | JAK2JAK1TYK2JAK3BCDIN3D | |
| SCHEMBL29498923 | 0.82 | JAK2 (0.36) | JAK2JAK1TYK2JAK3EP300 | |
| SCHEMBL29498964 | 0.81 | JAK2 (0.35) | JAK2JAK1TYK2JAK3EP300 | |
| SCHEMBL24327407 | 0.81 | IRAK1 (0.42) | JAK2JAK1TYK2JAK3EP300 | |
| SCHEMBL29498918 | 0.81 | JAK2 (0.37) | JAK2JAK1TYK2JAK3EP300 | |
| SCHEMBL29498943 | 0.79 | EP300 (0.31) | JAK2JAK1TYK2JAK3EP300 | |
| SCHEMBL24327939 | 0.77 | JAK2 (0.35) | JAK2JAK1TYK2JAK3RET | |
| SCHEMBL24328702 | 0.77 | JAK2 (0.35) | JAK2JAK1TYK2JAK3RET | |
| SCHEMBL29498944 | 0.76 | JAK2 (0.35) | JAK2JAK1TYK2JAK3RET | |
| SCHEMBL29498939 | 0.76 | JAK2 (0.35) | JAK2JAK1TYK2JAK3RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114369097-A | Heteroaromatic AhR inhibitors | 山东轩竹医药科技有限公司 | 2022-04-19 | — | — | CN | disclosed |