Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29078792 | 1.00 | L3MBTL1 (0.58) | L3MBTL1MAPTALDH1A1TP53TYR | |
| SCHEMBL27617775 | 0.83 | IKBKB (0.49) | L3MBTL1MAPTALDH1A1TSHRCYP1A2 | |
| SCHEMBL28530013 | 0.79 | KMT2A (0.50) | L3MBTL1MAPTALDH1A1TSHRNPC1 | |
| SCHEMBL29077108 | 0.75 | NPC1 (0.60) | L3MBTL1NPC1RAB9ACHRNB2CHRNB4 | |
| SCHEMBL845315 | 0.75 | L3MBTL1 (0.66) | L3MBTL1MAPTALDH1A1TP53TYR | |
| SCHEMBL28843620 | 0.75 | MKNK1 (0.45) | L3MBTL1MAPTALDH1A1TSHRHSD17B10 | |
| SCHEMBL2779146 | 0.74 | MAPT (1.00) | L3MBTL1MAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7156184 | 0.74 | MAPT (0.64) | L3MBTL1MAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7158819 | 0.74 | L3MBTL1 (0.64) | L3MBTL1MAPTALDH1A1TP53TYR | |
| SCHEMBL9390463 | 0.73 | MAPT (0.58) | L3MBTL1MAPTALDH1A1TP53TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232449-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087326-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-04-28 | — | — | WO | disclosed |