SCHEMBL29601744

SCHEMBL29601744

CC(C)C[C@H](N)C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)O)C(C)C)C(C)C)C(C)C

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 17/20 0.60
BACE2 Q9Y5Z0 2/20 0.59
CTSD P07339 2/20 0.57
CTSB P07858 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10790323 0.98 BACE1 (0.60) BACE1BACE2CTSD
SCHEMBL30130747 0.93 BACE1 (0.62) BACE1BACE2CTSD
SCHEMBL30051333 0.93 BACE1 (0.58) BACE1CTSDCTSB
SCHEMBL30051537 0.93 LTA4H (0.61)
SCHEMBL30258973 0.92 BACE1 (0.70) BACE1BACE2CTSD
SCHEMBL28860411 0.90 LTA4H (0.64)
SCHEMBL2185269 0.90 LTA4H (0.64)
SCHEMBL29519583 0.90 LTA4H (0.64)
SCHEMBL1864709 0.90 LTA4H (0.64)
SCHEMBL27517670 0.90 LTA4H (0.64)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621311-A Method for synthesizing cyclic heptapeptide Mortiamides and analogues thereof under assistance of DPKO carrier 西北工业大学 2022-06-14 CN disclosed