Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 8/20 | 0.40 |
| ▸ | CES1 | P23141 | 5/20 | 0.40 |
| ▸ | CES2 | O00748 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25969651 | 0.87 | HDAC1 (0.41) | CA14CES1CES2MEN1KMT2A | |
| SCHEMBL21010750 | 0.87 | HDAC1 (0.41) | CA14CES1CES2MEN1KMT2A | |
| SCHEMBL14802528 | 0.87 | HDAC1 (0.41) | CA14CES1CES2MEN1KMT2A | |
| SCHEMBL8736769 | 0.87 | HDAC1 (0.41) | CA14CES1CES2MEN1KMT2A | |
| SCHEMBL14396847 | 0.85 | CA14 (0.41) | CA14CES1CES2CTSKHDAC1 | |
| SCHEMBL5586260 | 0.83 | FAAH (0.50) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL5586210 | 0.83 | FAAH (0.50) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL16789557 | 0.82 | HDAC1 (0.38) | CA14MEN1KMT2AHSD17B10HDAC1 | |
| SCHEMBL2186961 | 0.80 | HDAC6 (0.39) | CA14CES2CTSKHDAC1HDAC2 | |
| SCHEMBL19466128 | 0.80 | CA14 (0.39) | CA14MEN1KMT2AHSD17B10CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685505-A | Imidazopyrrolopyridines as JAK family kinase inhibitors | 詹森药业有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-110312719-B | Imidazopyrrolopyridines as JAK family kinase inhibitors | 詹森药业有限公司 | 2022-04-15 | — | — | CN | disclosed |