Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668253 | 0.79 | ASAH1 (0.51) | ASAH1APAF1KMT2AHPGDHSD17B10 | |
| SCHEMBL4558108 | 0.73 | ASAH1 (0.50) | ASAH1APAF1KMT2AHPGDHSD17B10 | |
| SCHEMBL668254 | 0.73 | ASAH1 (0.50) | ASAH1APAF1KMT2AHPGDHSD17B10 | |
| SCHEMBL3795625 | 0.73 | HDAC8 (0.55) | ASAH1APAF1KMT2AHPGDHSD17B10 | |
| SCHEMBL8744445 | 0.73 | ASAH1 (0.62) | ASAH1KMT2AHPGDHSD17B10MEN1 | |
| SCHEMBL29145161 | 0.73 | ASAH1 (0.62) | ASAH1KMT2AHPGDHSD17B10MEN1 | |
| SCHEMBL7854777 | 0.72 | ASAH1 (0.51) | ASAH1KMT2AHPGDHSD17B10MEN1 | |
| SCHEMBL21388677 | 0.72 | ASAH1 (0.51) | ASAH1KMT2AHPGDHSD17B10MEN1 | |
| SCHEMBL21559595 | 0.72 | ASAH1 (0.51) | ASAH1KMT2AHPGDHSD17B10MEN1 | |
| SCHEMBL14740043 | 0.71 | MEN1 (0.48) | ASAH1APAF1KMT2AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119097698-A | Inhibitors of mevalonate pathway as efficient vaccine adjuvants | 清华大学 | 2024-12-10 | — | — | CN | disclosed |
| CN-114848656-B | Inhibitors of mevalonate pathway as efficient vaccine adjuvants | 清华大学 | 2024-09-27 | — | — | CN | disclosed |
| CN-114848656-A | Inhibitors of the mevalonate pathway as highly effective vaccine adjuvants | 清华大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-108289902-B | Inhibitors of the mevalonate pathway as highly effective vaccine adjuvants | 清华大学 | 2022-05-20 | — | — | CN | disclosed |