Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 15/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22770838 | 1.00 | CHRNA7 (0.47) | CHRNA7GRIN2BPIK3C3GRIN1PIK3CG | |
| SCHEMBL22770819 | 0.82 | GRIN1 (0.47) | GRIN2BGRIN1PIK3CG | |
| SCHEMBL12427703 | 0.81 | SLC6A4 (0.49) | CHRNA7PIK3C3 | |
| SCHEMBL4876885 | 0.78 | AXL (0.59) | PIK3C3PIK3CG | |
| SCHEMBL12427702 | 0.78 | CFTR (0.48) | GRIN2BPIK3C3GRIN1 | |
| SCHEMBL12427707 | 0.78 | SLC6A3 (0.57) | PIK3C3PIK3CG | |
| SCHEMBL5778713 | 0.77 | AXL (0.60) | PIK3C3PIK3CG | |
| SCHEMBL22770848 | 0.76 | GRIN2B (0.46) | GRIN2BGRIN1 | |
| SCHEMBL22770872 | 0.76 | GRIN1 (0.42) | CHRNA7GRIN2BGRIN1 | |
| SCHEMBL29603830 | 0.76 | GRIN1 (0.42) | CHRNA7GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983074-A1 | PYRIDINE CARBAMATES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2022-04-20 | — | — | EP | disclosed |