Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.45 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.45 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29604592 | 1.00 | SIGMAR1 (0.48) | SIGMAR1HDAC2HDAC8HDAC6KMT2A | |
| SCHEMBL23802861 | 0.83 | SIGMAR1 (0.41) | SIGMAR1KMT2A | |
| SCHEMBL23802847 | 0.83 | SIGMAR1 (0.41) | SIGMAR1KMT2A | |
| SCHEMBL8576442 | 0.81 | SIGMAR1 (0.49) | SIGMAR1HDAC2HDAC8HDAC6DRD2 | |
| SCHEMBL8576438 | 0.81 | SIGMAR1 (0.49) | SIGMAR1HDAC2HDAC8HDAC6DRD2 | |
| SCHEMBL17155200 | 0.81 | KMT2A (0.49) | SIGMAR1KMT2AL3MBTL1IDO1DRD2 | |
| SCHEMBL23802858 | 0.78 | TDP1 (0.49) | KMT2ADRD2MEN1GAA | |
| SCHEMBL12571328 | 0.78 | ABCB1 (0.54) | SIGMAR1L3MBTL1IDO1MAPT | |
| SCHEMBL28352440 | 0.78 | KMT2A (0.47) | KMT2AL3MBTL1DRD2NPFFR1NPFFR2 | |
| SCHEMBL30835197 | 0.78 | KMT2A (0.47) | KMT2AL3MBTL1DRD2NPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515896-B1 | CHIRAL CYCLEN COMPOUNDS AND THEIR USES | UNIV HONG KONG POLYTECHNIC (CN) | 2024-08-21 | — | — | EP | disclosed |
| US-11357873-B2 | Chiral cyclen compounds and their uses | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2022-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11357873-B2 | Chiral cyclen compounds and their uses | DCTN3, DCTN1, CDK3 | SIGMAR1 213/4885HDAC2 889/4885HDAC8 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.