Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 7/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 7/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 7/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 7/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | IL1RN | P18510 | 1/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.30 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14430310 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL19584901 | 0.89 | KDM4E (0.38) | KDM4EALDH1A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL12261417 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL20434223 | 0.83 | KDM4E (0.63) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL783668 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL29605666 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL5763704 | 0.76 | HSD17B1 (0.40) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL14430376 | 0.76 | PTGS1 (0.37) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL16555424 | 0.76 | KDM4E (0.36) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL29435935 | 0.76 | HSD17B1 (0.40) | KDM4EALDH1A1GLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125359-A1 | HETEROARYL COMPOUNDS AS MULTI-TARGET PROTEIN KINASE INHIBITORS | FUJIAN HAIXI PHARMACEUTICALS CO LTD (CN) | 2026-05-07 | — | — | US | disclosed |
| CN-109705191-B | IAP inhibitors and their use in medicine | 广东东阳光药业有限公司 | 2022-04-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125359-A1 | HETEROARYL COMPOUNDS AS MULTI-TARGET PROTEIN KINASE INHIBITORS | ERBB2, ERBB3, ARRB1 | KDM4E 3910/4885ALDH1A1 4063/4885GLA 2961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.