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Indolidan

Indolidan

SCHEMBL29605502

CC1(C)C(=O)Nc2ccc(C3=NNC(=O)CC3)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PDE3B Q13370 17/20 1.00
▸ PDE3A Q14432 17/20 1.00
▸ PDE4A P27815 13/20 1.00
▸ PDE4B Q07343 13/20 1.00
▸ PDE4C Q08493 13/20 1.00
▸ PDE4D Q08499 13/20 1.00
▸ PGR P06401 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indolidan SCHEMBL124043 1.00 PDE3B (1.00) PDE3BPDE3APDE4APDE4BPDE4C
SCHEMBL10518523 0.84 PDE3B (0.90) PDE3BPDE3APDE4APDE4BPDE4C
Indolidan SCHEMBL17076620 0.83 PDE3B (0.69) PDE3BPDE3APDE4APDE4BPDE4C
SCHEMBL7483850 0.83 PDE3B (0.70) PDE3BPDE3APDE4APDE4BPDE4C
SCHEMBL10520070 0.82 PDE3B (1.00) PDE3BPDE3APDE4APDE4BPDE4C
SCHEMBL10517412 0.82 PDE3B (1.00) PDE3BPDE3APDE4APDE4BPDE4C
SCHEMBL10572135 0.81 PDE3B (0.67) PDE3BPDE3APDE4APDE4BPDE4C
SCHEMBL7433571 0.80 PDE3B (0.67) PDE3BPDE3APDE4APDE4BPDE4C
SCHEMBL7427747 0.79 PDE3B (0.74) PDE3BPDE3APDE4APDE4BPDE4C
SCHEMBL7636343 0.78 PDE3B (0.64) PDE3BPDE3APDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114404588-A Compounds and methods for inhibiting phosphate transport 阿德利克斯公司 2022-04-29 — — CN disclosed