Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309462 | 1.00 | KDM4E (0.34) | KDM4ECYP1A2CYP2D6RAD52ADRB3 | |
| SCHEMBL9308713 | 1.00 | KDM4E (0.34) | KDM4ECYP1A2CYP2D6RAD52ADRB3 | |
| Hydrochloric Acid SCHEMBL3088634 | 0.99 | SMN1; SMN2 (0.34) | KDM4ECYP1A2CYP2D6RAD52ADRB3 | |
| Hydrochloric Acid SCHEMBL28265 | 0.99 | SMN1; SMN2 (0.34) | KDM4ECYP1A2CYP2D6RAD52ADRB3 | |
| Hydrochloric Acid SCHEMBL195167 | 0.98 | KDM4E (0.33) | KDM4ECYP1A2CYP2D6RAD52ADRB3 | |
| SCHEMBL15562859 | 0.88 | ADRB3 (0.35) | CYP1A2CYP2D6ADRB3CA12CA2 | |
| SCHEMBL9308678 | 0.88 | ADRB3 (0.35) | CYP1A2CYP2D6ADRB3CA12CA2 | |
| Hydrochloric Acid SCHEMBL3083869 | 0.86 | ADRB3 (0.35) | KDM4ECYP2D6ADRB3CA12CA2 | |
| Hydrochloric Acid SCHEMBL29377696 | 0.86 | ADRB3 (0.35) | KDM4ECYP2D6ADRB3CA12CA2 | |
| Hydrochloric Acid SCHEMBL3083871 | 0.86 | ADRB3 (0.35) | KDM4ECYP2D6ADRB3CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565965-B1 | Benzo b thiophen-5-yl derivative and process for producing the same | TOYAMA CHEMICAL CO LTD (JP) | 1996-11-13 | — | — | EP | claimed |
| US-5380878-A | Benzo[b]thiophen-5-yl derivative and process for producing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-01-10 | — | — | US | claimed |
| EP-0383281-B1 | 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO LTD (JP) | 1994-08-17 | — | — | EP | claimed |
| US-5280032-A | 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-01-18 | — | — | US | claimed |
| EP-0565965-A2 | Benzo b thiophen-5-yl derivative and process for producing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | claimed |
| EP-2389937-A1 | Medicinal composition for improving brain function | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-11-30 | — | — | EP | disclosed |
| US-8038956-B2 | Catalyzed soot filter manufacture and systems | BASF CORPORATION (US) | 2011-10-18 | — | — | US | disclosed |
| US-RE42327-E1 | Medicinal compositions improving brain function and method for improving brain function | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |
| US-7834053-B2 | Medicinal compositions improving brain function and method for improving brain function | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| US-20080103126-A1 | Medicinal compositions improving brain function and method for improving brian function | TOYAMA CHEMICAL CO., LTD. (JP) | 2008-05-01 | — | — | US | disclosed |
| US-7342043-B2 | synergistic antihypoxic mixture: acetylcholine esterase inhibitor (Donepezil and Tacrine) and neuroprotectant 1-[3-(2-(1-benzothiophen-5-yl)ethoxy)propyl]-3-azetidinol maleate; dysfunction of cerebral acetylcholine neurons in sequelae of cerebrovascular and senile dementia, Alzheimer's disease | TOYAMA CHEMICAL CO., LTD. (JP) | 2008-03-11 | — | — | US | disclosed |
| US-20050250843-A1 | Medicinal compositions improving brain function and method for improving brain function | TOYAMA CHEMICAL CO., LTD. (JP) | 2005-11-10 | — | — | US | disclosed |
| EP-1514542-A1 | MEDICINAL COMPOSITIONS IMPROVING BRAIN FUNCTION AND METHOD FOR IMPROVING BRAIN FUNCTION | TOYAMA CHEMICAL CO., LTD. (JP) | 2005-03-16 | — | — | EP | disclosed |
| EP-1020427-A1 | Agent for potentiating nerve growth factor activity containing 1,2-ethanediol derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0565965-B1 | Benzo b thiophen-5-yl derivative and process for producing the same | TOYAMA CHEMICAL CO LTD (JP) | 1996-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250843-A1 | Medicinal compositions improving brain function and method for improving brain function | CHRM2, ACHE, CHAT | KDM4E 588/4885CYP1A2 1445/4885CYP2D6 3084/4885 |
| US-20080103126-A1 | Medicinal compositions improving brain function and method for improving brian function | CHRM2, ACHE, CHRM1 | KDM4E 1323/4885CYP1A2 1623/4885CYP2D6 3065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.