SCHEMBL29608076

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)CC)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	13/20	0.54

▸	MAPK8	P45983	1/20	0.47

▸	MAPK9	P45984	1/20	0.47

▸	MAPK10	P53779	1/20	0.47

▸	F2	P00734	4/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29606801	0.97	REN (0.55)	RENMAPK8MAPK9MAPK10F2
SCHEMBL29608394	0.96	REN (0.49)	RENF2
SCHEMBL29607797	0.94	REN (0.49)	RENF2
SCHEMBL29607007	0.92	REN (0.47)	RENF2
SCHEMBL29608127	0.90	REN (0.49)	RENF2
SCHEMBL29607747	0.87	REN (0.54)	RENMAPK8MAPK9MAPK10
SCHEMBL29608153	0.86	REN (0.51)	RENF2
SCHEMBL29607579	0.85	SLC6A2 (0.49)	RENF2
SCHEMBL31518657	0.84	CALCR (0.58)	MAPK8MAPK9MAPK10F2
SCHEMBL29606993	0.83	REN (0.58)	RENF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20220120732-A1	TREATMENT OF DISEASES WITH MULTIMERIC PEPTIDES	RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL)	2022-04-21	—	—	US	disclosed