Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.61 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | REN | P00797 | 11/20 | 0.53 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | NPY4R | P50391 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607025 | 0.96 | MAPK8 (0.63) | MAPK8MAPK9MAPK10KEAP1REN | |
| SCHEMBL31462013 | 0.92 | MAPK8 (0.59) | MAPK8MAPK9MAPK10KEAP1REN | |
| SCHEMBL29607801 | 0.91 | MAPK8 (0.72) | MAPK8MAPK9MAPK10KEAP1REN | |
| SCHEMBL31462011 | 0.91 | MAPK8 (0.59) | MAPK8MAPK9MAPK10KEAP1REN | |
| SCHEMBL29416073 | 0.91 | KDM1A (0.57) | MAPK8MAPK9MAPK10KEAP1REN | |
| SCHEMBL29607286 | 0.90 | MAPK8 (0.66) | MAPK8MAPK9MAPK10KEAP1REN | |
| SCHEMBL29534390 | 0.89 | KDM1A (0.54) | MAPK8MAPK9MAPK10KEAP1KISS1R | |
| SCHEMBL31177227 | 0.88 | MAPK8 (0.60) | MAPK8MAPK9MAPK10KEAP1REN | |
| SCHEMBL31410829 | 0.88 | MAPK8 (0.62) | MAPK8MAPK9MAPK10KEAP1REN | |
| SCHEMBL31026121 | 0.88 | NPY4R (0.54) | KEAP1KISS1RKDM1ANPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220120732-A1 | TREATMENT OF DISEASES WITH MULTIMERIC PEPTIDES | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2022-04-21 | — | — | US | disclosed |