SCHEMBL29607286

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1)[C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK8	P45983	1/20	0.66

▸	MAPK9	P45984	1/20	0.66

▸	MAPK10	P53779	1/20	0.66

▸	REN	P00797	11/20	0.57

▸	KEAP1	Q14145	1/20	0.56

▸	KDM1A	O60341	3/20	0.56

▸	MAOB	P27338	1/20	0.50

▸	KDM5A	P29375	1/20	0.50

▸	KDM1B	Q8NB78	1/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29607908	0.96	MAPK8 (0.69)	MAPK8MAPK9MAPK10RENKEAP1
SCHEMBL29607801	0.92	MAPK8 (0.72)	MAPK8MAPK9MAPK10RENKEAP1
SCHEMBL31232415	0.92	KEAP1 (0.67)	MAPK8MAPK9MAPK10RENKEAP1
SCHEMBL29607740	0.90	MAPK8 (0.54)	MAPK8MAPK9MAPK10
SCHEMBL29608097	0.90	MAPK8 (0.61)	MAPK8MAPK9MAPK10RENKEAP1
SCHEMBL29607530	0.89	MAPK8 (0.74)	MAPK8MAPK9MAPK10RENKEAP1
SCHEMBL29607872	0.89	MAPK8 (0.59)	MAPK8MAPK9MAPK10REN
SCHEMBL29608298	0.89	MAPK8 (0.52)	MAPK8MAPK9MAPK10REN
SCHEMBL29666850	0.88	MAPK8 (0.62)	MAPK8MAPK9MAPK10KDM1A
SCHEMBL29666843	0.88	MAPK8 (0.63)	MAPK8MAPK9MAPK10KEAP1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20220120732-A1	TREATMENT OF DISEASES WITH MULTIMERIC PEPTIDES	RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL)	2022-04-21	—	—	US	disclosed