Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 11/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.46 |
| ▸ | USP1 | O94782 | 1/20 | 0.46 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.46 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.45 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19675773 | 1.00 | NTRK1 (0.51) | NTRK1CCNT1APPCLK4USP1 | |
| SCHEMBL29392704 | 0.88 | NTRK1 (0.62) | NTRK1CCNT1NTRK3NTRK2 | |
| SCHEMBL28713125 | 0.88 | NTRK1 (0.62) | NTRK1CCNT1NTRK3NTRK2 | |
| SCHEMBL22866364 | 0.86 | PDE2A (0.56) | APPCLK4USP1WDR48 | |
| SCHEMBL15584955 | 0.84 | NTRK1 (0.50) | NTRK1CCNT1APPCLK4AURKA | |
| SCHEMBL29695608 | 0.83 | MEN1 (0.46) | USP1WDR48 | |
| SCHEMBL7260597 | 0.83 | PDE5A (0.55) | APPUSP1WDR48 | |
| SCHEMBL25436239 | 0.80 | KDM5A (0.51) | NTRK1CCNT1APPAURKAJAK2 | |
| SCHEMBL18303253 | 0.80 | APP (0.47) | NTRK1CCNT1APPCLK4AURKA | |
| SCHEMBL15533833 | 0.80 | PDE4A (0.44) | CLK4JAK2LCKCLK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341145-B | Chemical compound | 博拉公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-3994142-A1 | CHEMICAL COMPOUNDS | Borah, Inc. (US) | 2022-05-11 | — | — | EP | disclosed |
| CN-114341145-A | Chemical compound | 博拉公司 | 2022-04-12 | — | — | CN | disclosed |