SCHEMBL29610281

SCHEMBL29610281

NC(=O)C(Cc1ccccc1)c1cccc(Cl)c1

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.71
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
TRPM8 Q7Z2W7 4/20 0.46
ACP3 P15309 1/20 0.45
GRIN2B Q13224 1/20 0.43
TP53 P04637 1/20 0.43
MAPT P10636 1/20 0.43
ADRB3 P13945 1/20 0.43
IDO1 P14902 1/20 0.43
TDO2 P48775 1/20 0.43
LMNA P02545 1/20 0.43
PNMT P11086 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28605536 1.00 EPHX1 (0.71) EPHX1MEN1KMT2ATRPM8ACP3
SCHEMBL29609873 0.91 EPHX1 (0.71) EPHX1MEN1KMT2AGRIN2BIDO1
SCHEMBL28919780 0.91 EPHX1 (0.71) EPHX1MEN1KMT2AGRIN2BIDO1
SCHEMBL8869646 0.88 MEN1 (0.64) EPHX1MEN1KMT2AACP3TP53
SCHEMBL3939264 0.84 EPHX1 (0.49) EPHX1MEN1KMT2AADRB3LMNA
SCHEMBL22758105 0.84 ADRB2 (0.49) EPHX1TP53MAPTADRB3
SCHEMBL1516139 0.84 EPHX1 (1.00) EPHX1ACP3
SCHEMBL11019097 0.83 EPHX1 (0.73) EPHX1LMNA
SCHEMBL621911 0.83 EPHX1 (0.73) EPHX1MEN1KMT2A
SCHEMBL10269752 0.83 EPHX1 (0.73) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113214104-B Method for synthesizing aromatic acetamide 浙江工业大学 2022-05-24 CN disclosed