Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 9/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373895 | 1.00 | KCNA3 (0.47) | KCNA3HTR1BKMT2ASLC6A4SLC6A2 | |
| SCHEMBL28373893 | 1.00 | KCNA3 (0.47) | KCNA3HTR1BKMT2ASLC6A4SLC6A2 | |
| SCHEMBL30600099 | 0.91 | KCNA3 (0.55) | KCNA3HTR1BKMT2ASLC6A4KDM4E | |
| SCHEMBL6675385 | 0.91 | KCNA3 (0.55) | KCNA3HTR1BKMT2ASLC6A4KDM4E | |
| SCHEMBL29376893 | 0.91 | KCNA3 (0.55) | KCNA3HTR1BKMT2ASLC6A4KDM4E | |
| SCHEMBL9291677 | 0.91 | KCNA3 (0.55) | KCNA3HTR1BKMT2ASLC6A4KDM4E | |
| SCHEMBL30600096 | 0.91 | KCNA3 (0.55) | KCNA3HTR1BKMT2ASLC6A4KDM4E | |
| SCHEMBL6678503 | 0.91 | KCNA3 (0.55) | KCNA3HTR1BKMT2ASLC6A4KDM4E | |
| SCHEMBL29609193 | 0.81 | HTR1B (0.49) | KCNA3HTR1BKMT2ASLC6A4SLC6A2 | |
| SCHEMBL28369921 | 0.81 | HTR1B (0.49) | KCNA3HTR1BKMT2ASLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110937984-B | Dapoxetine hydrochloride related substance, preparation method and application thereof | 苏州科伦药物研究有限公司 | 2022-05-03 | — | — | CN | disclosed |