Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 9/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.51 |
| ▸ | HTR1D | P28221 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678503 | 1.00 | KCNA3 (0.55) | KCNA3HTR1BKDM4EKMT2AMEN1 | |
| SCHEMBL9291677 | 1.00 | KCNA3 (0.55) | KCNA3HTR1BKDM4EKMT2AMEN1 | |
| SCHEMBL30600099 | 1.00 | KCNA3 (0.55) | KCNA3HTR1BKDM4EKMT2AMEN1 | |
| SCHEMBL30600096 | 1.00 | KCNA3 (0.55) | KCNA3HTR1BKDM4EKMT2AMEN1 | |
| SCHEMBL29376893 | 1.00 | KCNA3 (0.55) | KCNA3HTR1BKDM4EKMT2AMEN1 | |
| SCHEMBL28373893 | 0.91 | KCNA3 (0.47) | KCNA3HTR1BKDM4EKMT2AMEN1 | |
| SCHEMBL29610288 | 0.91 | KCNA3 (0.47) | KCNA3HTR1BKDM4EKMT2AMEN1 | |
| SCHEMBL28373895 | 0.91 | KCNA3 (0.47) | KCNA3HTR1BKDM4EKMT2AMEN1 | |
| SCHEMBL9292084 | 0.88 | SLC6A4 (0.50) | KCNA3HTR1BKDM4EKMT2AMEN1 | |
| SCHEMBL28331986 | 0.84 | CYP1A2 (0.64) | KCNA3HTR1BKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116715593-A | Optimized preparation method of dapoxetine hydrochloride and intermediate thereof | 北京悦康科创医药科技股份有限公司 | 2023-09-08 | — | — | CN | claimed |
| CN-109438555-B | Preparation method of non-natural antioxidant peptide | 浙江海洋大学 | 2022-07-29 | — | — | CN | claimed |
| CN-109170130-B | Method for preparing fish meal by solid-state fermentation of aquatic product leftovers | 浙江炯炜海洋生物科技有限公司 | 2022-02-08 | — | — | CN | claimed |
| CN-113861046-A | Preparation method of dapoxetine impurity reference substance | 南京卓康医药科技有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-109182132-B | Method for culturing Alexandrium micranthum producing gonyautoxin | 浙江海洋大学 | 2021-09-14 | — | — | CN | claimed |
| CN-109503397-A | A kind of synthetic method of Dapoxetine hydrochloride | 华控创新（北京）药物研究院有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-109438555-A | A kind of preparation method of novel non-natural anti-oxidation peptide | 浙江海洋大学 | 2019-03-08 | — | — | CN | claimed |
| CN-105461573-A | Preparation method of (S)-N-demethyl dapoxetine | CHONGQING KANGLE PHARMACEUTICAL CO LTD | 2016-04-06 | — | — | CN | claimed |
| CN-104628584-A | High-purity dapoxetine preparation method suitable for industrialization | GUANGZHOU REGENEX CORP | 2015-05-20 | — | — | CN | claimed |
| WO-2014024205-A1 | A METHOD FOR PREPARING (S)-(+)-N, N-DIMETHYL-3-(NAPHTHALEN-1-YLOXY)-1-PHENYLPROPAN-1-AMINE OR ITS SALT AND INTERMEDIATE THEREOF | R L FINE CHEM (IN) | 2014-02-13 | — | — | WO | claimed |
| CN-102442891-A | Preparation method of dapoxetine intermediate compound | CHIRAL QUEST BIOCHEMICAL SUZHOU CO LTD | 2012-05-09 | — | — | CN | claimed |
| CN-100402488-C | Synthetic method for dapoxetine | SHANGHAI MAYAO CHEMICAL TECHNO (CN) | 2008-07-16 | — | — | CN | claimed |
| CN-1821212-A | Synthetic method for dapoxetine | MAYAO CHEMICAL TECHNOLOGY CO L (CN) | 2006-08-23 | — | — | CN | claimed |
| CN-116715593-A | Optimized preparation method of dapoxetine hydrochloride and intermediate thereof | 北京悦康科创医药科技股份有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-109438555-B | Preparation method of non-natural antioxidant peptide | 浙江海洋大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-109170130-B | Method for preparing fish meal by solid-state fermentation of aquatic product leftovers | 浙江炯炜海洋生物科技有限公司 | 2022-02-08 | — | — | CN | disclosed |
| EP-1465726-A1 | PROCESS FOR PREPARING NONRACEMIC CHIRAL ALCOHOLS | DSM IP Assets B.V. (NL) | 2004-10-13 | — | — | EP | disclosed |
| US-20030171213-A1 | Process for preparing nonracemic chiral alcohols | DSM N.V. (NL) | 2003-09-11 | — | — | US | disclosed |
| WO-2003061824-A1 | PROCESS FOR PREPARING NONRACEMIC CHIRAL ALCOHOLS | DSM IP ASSETS B.V. (NL) | 2003-07-31 | — | — | WO | disclosed |
| US-5292962-A | Intermediates to 1-phenyl-3-naphthalenyloxy-propanamines | ELI LILLY AND COMPANY (US) | 1994-03-08 | — | — | US | disclosed |