Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.59 |
| ▸ | MTOR | P42345 | 12/20 | 0.59 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.56 |
| ▸ | PI4KA | P42356 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462714 | 1.00 | PIK3CA (0.59) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL30333881 | 1.00 | PIK3CA (0.59) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL22447698 | 0.89 | PIK3CA (0.53) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL30902253 | 0.88 | PIK3CA (0.55) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL742722 | 0.88 | PIK3CA (0.49) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL15555632 | 0.87 | PIK3CA (0.56) | PIK3CAMTORPIK3R1PIK3CGPI4KA | |
| SCHEMBL16683557 | 0.87 | PIK3CA (0.63) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL30902213 | 0.87 | PIK3CA (0.56) | PIK3CAMTORPIK3R1PIK3CGPI4KA | |
| SCHEMBL30333513 | 0.86 | PI4KA (0.46) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL9953017 | 0.86 | PI4KA (0.53) | PIK3CAMTORPIK3R1PIK3CGPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135913-B | 3-substituent-6-pyridine substituent-six-membered and five-membered heterocyclic derivative and preparation method and application thereof | 沈阳药科大学 | 2022-05-24 | — | — | CN | disclosed |