Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.52 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.52 |
| ▸ | MTOR | P42345 | 2/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.52 |
| ▸ | CCR4 | P51679 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30333881 | 0.88 | PIK3CA (0.59) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL462714 | 0.88 | PIK3CA (0.59) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL29610307 | 0.88 | PIK3CA (0.59) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL22447740 | 0.88 | ACLY (0.46) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL22447679 | 0.87 | PIK3CA (0.49) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL22447379 | 0.85 | MEN1 (0.50) | PIK3CA | |
| SCHEMBL2919328 | 0.84 | PIK3CD (0.54) | PIK3CAPIK3CDPIK3CBMTORPIK3CG | |
| SCHEMBL15556197 | 0.82 | MTOR (0.55) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL22447736 | 0.81 | CCR4 (0.64) | CCR4 | |
| SCHEMBL22447698 | 0.81 | PIK3CA (0.53) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957219-A | Pyridine derivative and application thereof | 四川汇宇制药股份有限公司 | 2024-04-30 | — | — | CN | disclosed |