⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19673289 | 0.92 | — | — | |
| SCHEMBL21695136 | 0.90 | KDM4E (0.76) | — | |
| SCHEMBL10560389 | 0.83 | — | — | |
| SCHEMBL1900471 | 0.83 | KDM4E (0.82) | — | |
| SCHEMBL860791 | 0.83 | KDM4E (0.94) | — | |
| SCHEMBL1446623 | 0.81 | — | — | |
| SCHEMBL14739904 | 0.80 | KDM4E (1.00) | — | |
| SCHEMBL1900654 | 0.80 | KDM4E (1.00) | — | |
| SCHEMBL14740196 | 0.80 | KDM4E (1.00) | — | |
| SCHEMBL1847535 | 0.80 | KDM4E (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180066011-A1 | METHOD FOR PREPARING SITE-SPECIFICALLY MODIFIED PROTEIN BASED ON NOVEL CARBON-CARBON BOND FORMATION | PROMEDIGEN (KR) | 2018-03-08 | — | — | US | claimed |
| US-10723760-B2 | Method for preparing site-specifically modified protein based on novel carbon-carbon bond formation | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-07-28 | — | — | US | disclosed |
| WO-2018044130-A1 | NOVEL METHOD FOR PRODUCING PROTEIN HAVING A CARBON-CARBON BOND-BASED SITE-SPECIFIC MODIFICATION | 한국과학기술원 | 2018-03-08 | — | — | WO | disclosed |
| US-20180066011-A1 | METHOD FOR PREPARING SITE-SPECIFICALLY MODIFIED PROTEIN BASED ON NOVEL CARBON-CARBON BOND FORMATION | PROMEDIGEN (KR) | 2018-03-08 | — | — | US | disclosed |
| US-20160326212-A1 | Chemical Modification of Proteins | R.P. SCHERER TECHNOLOGIES, LLC | 2016-11-10 | — | — | US | disclosed |
| US-9346851-B2 | Chemical modification of proteins | R.P. SCHERER TECHNOLOGIES, LLC (US) | 2016-05-24 | — | — | US | disclosed |
| WO-2014209980-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2014-12-31 | — | — | WO | disclosed |
| EP-2254900-B1 | CHEMICAL MODIFICATION OF PROTEINS | ISIS INNOVATION (GB) | 2012-03-14 | — | — | EP | disclosed |
| US-20110144304-A1 | Chemical Modification of Proteins | REDWOOD BIOSCIENCE, INC. | 2011-06-16 | — | — | US | disclosed |
| EP-2254900-A1 | CHEMICAL MODIFICATION OF PROTEINS | ISIS Innovation Limited (GB) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009103941-A1 | CHEMICAL MODIFICATION OF PROTEINS | ISIS INNOVATION LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |