Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2967793 | 0.93 | PRLHR (0.33) | DPP4ALDH1A1MAPT | |
| SCHEMBL2952804 | 0.93 | DPP4 (0.35) | DPP4TSHRFAPALDH1A1MAPT | |
| SCHEMBL2965594 | 0.92 | ALDH1A1 (0.34) | DPP4TSHRALDH1A1GAAMAPT | |
| SCHEMBL2952643 | 0.90 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| SCHEMBL2958725 | 0.90 | DPP4 (0.33) | DPP4FAP | |
| SCHEMBL2962138 | 0.88 | DPP4 (0.37) | DPP4FAP | |
| SCHEMBL2964155 | 0.87 | HTR2C (0.38) | DPP4FAPALDH1A1HIF1A | |
| SCHEMBL2964934 | 0.87 | DPP4 (0.35) | DPP4FAP | |
| SCHEMBL2958637 | 0.86 | PDE5A (0.32) | DPP4 | |
| SCHEMBL2954374 | 0.85 | DPP4 (0.32) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772226-B2 | Condensed imidazole derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| US-20090018331-A1 | CONDENSED IMIDAZOLE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-01-15 | — | — | US | disclosed |
| US-20060063787-A1 | Condensed imidazole derivatives | EISAI CO., LTD. (JP) | 2006-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063787-A1 | Condensed imidazole derivatives | DPP4, HDAC1, DPP7 | DPP4 1/4885TSHR 1385/4885FAP 3205/4885 |
| US-20090018331-A1 | CONDENSED IMIDAZOLE DERIVATIVES | DPP4, HDAC1, DPP7 | DPP4 1/4885TSHR 1385/4885FAP 3205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.