⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopropane Carboxylic Acid SCHEMBL4643 | 0.96 | — | — | |
| SCHEMBL196124 | 0.96 | TSHR (0.61) | — | |
| Cyclopropane Carboxylic Acid SCHEMBL5499291 | 0.96 | — | — | |
| SCHEMBL329128 | 0.96 | TSHR (0.61) | — | |
| SCHEMBL26833 | 0.96 | TSHR (0.61) | — | |
| Cyclopropane Carboxylic Acid SCHEMBL32889332 | 0.96 | — | — | |
| Cyclopropane Carboxylic Acid SCHEMBL10800712 | 0.96 | — | — | |
| SCHEMBL36093 | 0.96 | TSHR (0.61) | — | |
| SCHEMBL20262978 | 0.92 | TSHR (0.58) | — | |
| Cyclopropane Carboxylic Acid SCHEMBL9879479 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106316824-B | A kind of new method of synthesis 2- fluorine cyclopropane-carboxylic acids | 广州康瑞泰药业有限公司 | 2018-10-19 | — | — | CN | disclosed |
| US-8476445-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| US-20100137605-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-7678915-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-03-16 | — | — | US | disclosed |
| US-20070010677-A1 | Process for production of piperidine derivatives | AMR TECHNOLOGY, INC. (US) | 2007-01-11 | — | — | US | disclosed |
| US-20050209279-A1 | Process for production of piperidine derivatives | AMR TECHNOLOGY, INC. (US) | 2005-09-22 | — | — | US | disclosed |
| US-6919458-B2 | Process for production of piperidine derivatives | AMR TECHNOLOGY, INC. (US) | 2005-07-19 | — | — | US | disclosed |
| EP-0868182-B1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RES INC (US) | 2003-09-03 | — | — | EP | disclosed |
| US-20030028029-A1 | Process for production of piperidine derivatives | BARCLAYS BANK PLC, AS THE COLLATERAL AGENT | 2003-02-06 | — | — | US | disclosed |
| US-6458958-B1 | PROCESS OF PREPARING A PIPERIDINE DERIVATIVE COMPOUND OF THE FORMULA: ACYLATING AN .ALPHA.,.ALPHA.-DISUBSTITUTED-METHYLBENZENE DERIVATIVE HAVING THE FORMULA: | ALBANY MOLECULAR RESEARCH, INC. | 2002-10-01 | — | — | US | disclosed |
| US-6444824-B1 | ANTISEROTONINE AGENTS; SIDE EFFECT REDUCTION | ALBANY MOLECULAR RESEARCH, INC. | 2002-09-03 | — | — | US | disclosed |
| US-6153754-A | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0868182-A4 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RES INC (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0868182-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 1998-10-07 | — | — | EP | disclosed |
| WO-1997023213-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 1997-07-03 | — | — | WO | disclosed |
| US-4555370-A | CYANTATION OF ACYL. FLUORIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-26 | — | — | US | disclosed |