⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopropane Carboxylic Acid SCHEMBL32889332 | 0.96 | — | — | |
| SCHEMBL196124 | 0.96 | TSHR (0.61) | — | |
| Cyclopropane Carboxylic Acid SCHEMBL5499291 | 0.96 | — | — | |
| Cyclopropane Carboxylic Acid SCHEMBL4643 | 0.96 | — | — | |
| Cyclopropane Carboxylic Acid SCHEMBL10800712 | 0.96 | — | — | |
| SCHEMBL26833 | 0.96 | TSHR (0.61) | — | |
| SCHEMBL329128 | 0.96 | TSHR (0.61) | — | |
| SCHEMBL36093 | 0.96 | TSHR (0.61) | — | |
| SCHEMBL20262978 | 0.92 | TSHR (0.58) | — | |
| Hydrochloric Acid SCHEMBL890381 | 0.92 | TSHR (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011959-A | 1,2-diaminocyclohexane-platinum complexes with antitumor activity | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0333756-A1 | 1,2-DIAMINOCYCLOHEXANE-PLATINUM COMPLEXES WITH ANTITUMOR ACTIVITY. | UNIV TEXAS (US) | 1989-09-27 | — | — | EP | disclosed |
| EP-0130482-B1 | DIAMINOCYCLOHEXANE PLATINUM COMPLEXES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Research Corporation (US) | 1988-12-28 | — | — | EP | disclosed |
| US-4758588-A | Diaminocyclohexane platinum complexes | RESEARCH CORPORATION TECHNOLOGIES (US) | 1988-07-19 | — | — | US | disclosed |
| WO-1988003925-A1 | 1,2-DIAMINOCYCLOHEXANE-PLATINUM COMPLEXES WITH ANTITUMOR ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1988-06-02 | — | — | WO | disclosed |
| US-4661516-A | WATER SOLUBLE, ANTITUMOR AGENTS | RESEARCH CORPORATION (US) | 1987-04-28 | — | — | US | disclosed |
| EP-0130482-A1 | Diaminocyclohexane platinum complexes, process for preparing same and pharmaceutical compositions containing same | Research Corporation (US) | 1985-01-09 | — | — | EP | disclosed |