Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MYOC | Q99972 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.44 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16345403 | 1.00 | HSPB1 (0.64) | HSPB1LMNARAB9AHTTMAPT | |
| SCHEMBL12872523 | 0.80 | HSPB1 (0.54) | HSPB1LMNARAB9AHTTMAPT | |
| SCHEMBL11478740 | 0.80 | HSPB1 (0.54) | HSPB1LMNARAB9AHTTMAPT | |
| SCHEMBL177869 | 0.80 | HTT (0.58) | HSPB1LMNARAB9AHTTMAPT | |
| SCHEMBL5565238 | 0.80 | HSPB1 (0.49) | HSPB1LMNAHTTMAPTMEN1 | |
| SCHEMBL5571120 | 0.80 | PDE7A (0.61) | HSPB1LMNARAB9AMAPTMEN1 | |
| SCHEMBL30929726 | 0.80 | HSPB1 (0.49) | HSPB1LMNAHTTMAPTMEN1 | |
| SCHEMBL1163154 | 0.80 | KMT2A (0.53) | HSPB1LMNARAB9AMAPTMEN1 | |
| SCHEMBL29696525 | 0.80 | KMT2A (0.53) | HSPB1LMNARAB9AMAPTMEN1 | |
| SCHEMBL11689190 | 0.80 | HSPB1 (0.79) | HSPB1LMNARAB9AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440515-B | Substituted benzofuranyl and benzoxazolyl compounds and uses thereof | 卡尔约药物治疗公司 | 2022-05-03 | — | — | CN | disclosed |