Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 17/20 | 0.57 |
| ▸ | HTR1A | P08908 | 8/20 | 0.55 |
| ▸ | DRD2 | P14416 | 4/20 | 0.54 |
| ▸ | DRD5 | P21918 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1232169 | 1.00 | HTR7 (0.57) | HTR7HTR1ADRD2DRD5DRD3 | |
| SCHEMBL9049355 | 0.87 | HTR7 (0.63) | HTR7HTR1ADRD2DRD5DRD3 | |
| SCHEMBL27451951 | 0.85 | HTR7 (0.53) | HTR7HTR1ADRD2DRD5DRD3 | |
| SCHEMBL5999408 | 0.82 | HTR7 (0.57) | HTR7HTR1ADRD2DRD5DRD3 | |
| SCHEMBL8240109 | 0.82 | HTR7 (0.57) | HTR7HTR1ADRD2DRD5DRD3 | |
| SCHEMBL6696116 | 0.82 | HTR7 (0.57) | HTR7HTR1ADRD2DRD5DRD3 | |
| SCHEMBL4656369 | 0.82 | HTR7 (0.57) | HTR7HTR1ADRD2DRD5DRD3 | |
| SCHEMBL3227442 | 0.82 | HTR7 (0.57) | HTR7HTR1ADRD2DRD5DRD3 | |
| SCHEMBL318502 | 0.82 | HTR7 (0.57) | HTR7HTR1ADRD2DRD5DRD3 | |
| SCHEMBL28298254 | 0.81 | HTR7 (0.54) | HTR7HTR1ADRD2DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114671880-B | Synthesis and application of indole-2, 3-dinitrile antitumor compounds containing fatty amino | 大连理工大学 | 2023-06-06 | — | — | CN | claimed |
| CN-117567351-A | Preparation method of 4- (2-bromoethyl) -1, 3-dihydro-2H-indol-2-one | 常州锐博生物科技有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-114671880-B | Synthesis and application of indole-2, 3-dinitrile antitumor compounds containing fatty amino | 大连理工大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-112745256-B | Preparation method of 4- (2-bromoethyl) -1, 3-dihydro-2H-indol-2-one | 常州锐博生物科技有限公司 | 2022-03-11 | — | — | CN | disclosed |