Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CTSV | O60911 | 1/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28133652 | 1.00 | HPGD (1.00) | HPGDSMN1; SMN2HTTMAPK1MEN1 | |
| SCHEMBL1173520 | 1.00 | HPGD (1.00) | HPGDSMN1; SMN2HTTMAPK1MEN1 | |
| SCHEMBL8987418 | 0.85 | HPGD (0.74) | HPGDSMN1; SMN2HTTMAPK1MEN1 | |
| SCHEMBL8987046 | 0.85 | HPGD (0.74) | HPGDSMN1; SMN2HTTMAPK1MEN1 | |
| SCHEMBL8986955 | 0.85 | HPGD (0.74) | HPGDSMN1; SMN2HTTMAPK1MEN1 | |
| SCHEMBL8987475 | 0.83 | HPGD (0.70) | HPGDSMN1; SMN2HTTMAPK1MEN1 | |
| SCHEMBL8987096 | 0.83 | HPGD (0.70) | HPGDSMN1; SMN2HTTMAPK1MEN1 | |
| SCHEMBL12871194 | 0.82 | HPGD (0.69) | HPGDSMN1; SMN2HTTMAPK1MEN1 | |
| SCHEMBL8986966 | 0.81 | KDM4E (0.71) | HPGDSMN1; SMN2HTTMAPK1MEN1 | |
| SCHEMBL31677372 | 0.81 | KDM4E (0.71) | HPGDSMN1; SMN2HTTMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825722-B | Saturated red-light-emitting fluorenyl benzoquinoline iridium complex | 北京印刷学院 | 2023-06-09 | — | — | CN | claimed |
| EP-4355330-A1 | EGFR INHIBITOR AND PERK ACTIVATOR IN COMBINATION THERAPY AND THEIR USE FOR TREATING CANCER | Genentech, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| CN-111825722-B | Saturated red-light-emitting fluorenyl benzoquinoline iridium complex | 北京印刷学院 | 2023-06-09 | — | — | CN | disclosed |
| WO-2022265950-A1 | EGFR INHIBITOR AND PERK ACTIVATOR IN COMBINATION THERAPY AND THEIR USE FOR TREATING CANCER | GENENTECH, INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| CN-110248934-B | Heteroaryl PAD4 inhibitors | 帕德罗科治疗公司 | 2022-05-24 | — | — | CN | disclosed |