SCHEMBL29612224

SCHEMBL29612224

O=C1c2ccccc2C(=O)c2c1ccc1ccccc21

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 2/20 0.78
MEN1 O00255 5/20 0.65
KMT2A Q03164 5/20 0.65
ALDH1A1 P00352 5/20 0.65
MAPT P10636 3/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
RAB9A P51151 2/20 0.65
MAPK1 P28482 4/20 0.50
MAOA P21397 3/20 0.50
CYP3A4 P08684 3/20 0.50
MCL1 Q07820 2/20 0.50
HPGD P15428 2/20 0.50
ALOX12 P18054 2/20 0.50
NSD2 O96028 1/20 0.50
OPRM1 P35372 1/20 0.50
OPRD1 P41143 1/20 0.50
HKDC1 Q2TB90 1/20 0.50
MAOB P27338 1/20 0.50
CDC25B P30305 1/20 0.50
KDM4E B2RXH2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29411157 1.00 DNMT1 (0.78) DNMT1MEN1KMT2AALDH1A1MAPT
SCHEMBL183078 1.00 DNMT1 (0.78) DNMT1MEN1KMT2AALDH1A1MAPT
SCHEMBL29358121 1.00 DNMT1 (0.78) DNMT1MEN1KMT2AALDH1A1MAPT
SCHEMBL7122517 0.94 DNMT1 (0.73) DNMT1MEN1KMT2AALDH1A1MAPT
SCHEMBL30375875 0.92 DNMT1 (0.92) DNMT1MEN1KMT2AALDH1A1MAPT
SCHEMBL2175783 0.92 DNMT1 (0.92) DNMT1MEN1KMT2AALDH1A1MAPT
SCHEMBL29440308 0.92 DNMT1 (0.92) DNMT1MEN1KMT2AALDH1A1MAPT
SCHEMBL3922177 0.92 DNMT1 (0.71) DNMT1MEN1KMT2AALDH1A1MAPT
SCHEMBL29466071 0.92 DNMT1 (0.71) DNMT1MEN1KMT2AALDH1A1MAPT
SCHEMBL9900718 0.91 DNMT1 (0.70) DNMT1MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109983595-B Composition for organic electronic device encapsulant and encapsulant formed using the same 莫门蒂夫性能材料韩国株式会社 2023-04-04 CN disclosed
CN-111825364-B Preparation method of environment-friendly naphthalene water reducer 安徽鑫固环保股份有限公司 2022-06-14 CN disclosed