SCHEMBL3922177

SCHEMBL3922177

O=C1c2ccccc2-c2c1ccc1ccccc21

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 2/20 0.71
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
ALDH1A1 P00352 4/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
MAPT P10636 3/20 0.60
RAB9A P51151 2/20 0.60
NSD2 O96028 1/20 0.50
OPRM1 P35372 1/20 0.50
OPRD1 P41143 1/20 0.50
HKDC1 Q2TB90 1/20 0.50
CDC25B P30305 1/20 0.50
CES1 P23141 3/20 0.47
HPGD P15428 2/20 0.46
ALOX12 P18054 2/20 0.46
MAPK1 P28482 2/20 0.46
PTPN1 P18031 1/20 0.46
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
TP53 P04637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466071 1.00 DNMT1 (0.71) DNMT1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL19230424 0.96 DNMT1 (0.78) DNMT1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL183078 0.92 DNMT1 (0.78) DNMT1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL29411157 0.92 DNMT1 (0.78) DNMT1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL29358121 0.92 DNMT1 (0.78) DNMT1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL29612224 0.92 DNMT1 (0.78) DNMT1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL12236188 0.89 DNMT1 (0.67) DNMT1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL30362207 0.89 DNMT1 (0.67) DNMT1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL9900718 0.87 DNMT1 (0.70) DNMT1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL16144669 0.85 DNMT1 (0.68) DNMT1MEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4661297-A ANTILEUKEMIA AGENTS; IMMUNOSUPPRESSIVE AGENTS SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) 1987-04-28 US claimed
CN-118027362-A Benzofluorenone polymer and preparation method and application thereof 五邑大学 2024-05-14 CN disclosed
EP-3635056-B1 LIGHT COLOR ROSIN ESTER COMPOSITIONS AND METHODS OF MAKING SAME KRATON POLYMERS LLC (US) 2024-04-10 EP disclosed
CN-117447436-A Spiropyran derivative, color-changing glass paint and preparation method and application thereof 广州市科涵实业有限责任公司 2024-01-26 CN disclosed
CN-111349397-B Pale rosin and rosin ester compositions 科腾聚合物有限责任公司 2023-09-12 CN disclosed
US-20230247898-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-08-03 US disclosed
US-20230247898-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-08-03 US disclosed
US-20230213863-A1 COMPOUND, RESIST UNDERLAYER FILM COMPOSITION INCLUDING SAME, AND RESIST UNDERLAYER FILM DONGJIN SEMICHEM CO., LTD. (KR) 2023-07-06 US disclosed
US-20230213863-A1 COMPOUND, RESIST UNDERLAYER FILM COMPOSITION INCLUDING SAME, AND RESIST UNDERLAYER FILM DONGJIN SEMICHEM CO., LTD. (KR) 2023-07-06 US disclosed
US-11653562-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-05-16 US disclosed
US-20080233429-A1 Polymer Compound and Polymer Light-Emitting Device Using the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-25 US disclosed
US-20080145571-A1 Polymer Compound And Polymer Light Emitting Device Using The Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-06-19 US disclosed
US-20080145571-A1 Polymer Compound And Polymer Light Emitting Device Using The Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-06-19 US disclosed
WO-2007140071-A1 PHOTOCHROMIC MATERIALS COMPRISING HALOALKYL GROUPS TRANSITIONS OPTICAL, INC. (US) 2007-12-06 WO disclosed
US-20070278460-A1 Photochromic materials comprising metallocenyl groups TRANSITIONS OPTICAL LIMITED (IE) 2007-12-06 US disclosed
WO-2007140058-A1 PHOTOCHROMIC MATERIALS COMPRISING METALLOCENYL GROUPS TRANSITIONS OPTICAL, INC. (US) 2007-12-06 WO disclosed
US-20070278461-A1 PHOTOCHROMIC MATERIALS COMPRISING HALOALKYL GROUPS TRANSITIONS OPTICAL, INC. (US) 2007-12-06 US disclosed
US-4661297-A ANTILEUKEMIA AGENTS; IMMUNOSUPPRESSIVE AGENTS SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) 1987-04-28 US disclosed
US-4661297-A ANTILEUKEMIA AGENTS; IMMUNOSUPPRESSIVE AGENTS SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) 1987-04-28 US disclosed
US-4661297-A ANTILEUKEMIA AGENTS; IMMUNOSUPPRESSIVE AGENTS SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) 1987-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11653562-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same OPA1, ODC1, TMEM109 DNMT1 326/4885MEN1 1160/4885KMT2A 2798/4885
US-20070278461-A1 PHOTOCHROMIC MATERIALS COMPRISING HALOALKYL GROUPS TELO2, EYA3, CRY2 DNMT1 2282/4885MEN1 4496/4885KMT2A 774/4885
US-20230247898-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OPA1, ODC1, TMEM109 DNMT1 326/4885MEN1 1160/4885KMT2A 2798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.