Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4465625 | 0.87 | EDNRB (0.35) | EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL29612340 | 0.86 | EDNRB (0.35) | EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL29612286 | 0.85 | SYK (0.33) | EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL5952168 | 0.85 | SYK (0.33) | EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL2525982 | 0.84 | PDCD1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL29564499 | 0.84 | PDCD1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL8630711 | 0.83 | PDCD1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL29612269 | 0.83 | EDNRB (0.33) | EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL7598771 | 0.82 | EDNRB (0.36) | EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL17698566 | 0.81 | CYP1A2 (0.38) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915824-B1 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2022-05-25 | — | — | EP | claimed |
| EP-2915824-B1 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2022-05-25 | — | — | EP | disclosed |