Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 3/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.39 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.39 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28732809 | 1.00 | ERN1 (0.46) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL29464785 | 0.86 | MAOA (0.48) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL15698829 | 0.80 | CYP11B1 (0.44) | ALDH1A1RAB9AMAOAPDE2APDE10A | |
| SCHEMBL3677398 | 0.80 | ERN1 (0.56) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL17178323 | 0.79 | PDE2A (0.51) | NFE2L2RAB9ANPC1PDE2APDE10A | |
| SCHEMBL17178265 | 0.79 | PDE2A (0.53) | ALDH1A1RAB9AMEN1NPC1KMT2A | |
| SCHEMBL20595575 | 0.78 | HSP90AA1 (0.44) | NFE2L2RAB9AMEN1KMT2APDE2A | |
| SCHEMBL28476090 | 0.75 | ERN1 (0.50) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL7608317 | 0.74 | PDE2A (0.44) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL14840763 | 0.73 | ERN1 (0.51) | ERN1ALDH1A1TRIM24TYRTRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466913-B | Dihydro quinoline photochromic compounds | 光学转变有限公司 | 2024-07-30 | — | — | CN | disclosed |
| EP-4034610-A1 | DIHYDROQUINOLINE PHOTOCHROMIC COMPOUNDS | Transitions Optical, Ltd. (IE) | 2022-08-03 | — | — | EP | disclosed |
| CN-114466913-A | Dihydroquinoline photochromic compounds | 光学转变有限公司 | 2022-05-10 | — | — | CN | disclosed |