Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23178256 | 1.00 | HSD11B1 (0.39) | HSD11B1HTTSMN1; SMN2MAPTLMNA | |
| SCHEMBL23178114 | 0.91 | ACP1 (0.36) | HSD11B1HTTSMN1; SMN2ABCG2 | |
| SCHEMBL29613281 | 0.91 | ACP1 (0.36) | HSD11B1HTTSMN1; SMN2ABCG2 | |
| SCHEMBL29613271 | 0.81 | HTT (0.35) | HSD11B1HTTSMN1; SMN2MAPTRAB9A | |
| SCHEMBL23178110 | 0.81 | HTT (0.35) | HSD11B1HTTSMN1; SMN2MAPTRAB9A | |
| SCHEMBL23178101 | 0.80 | HTT (0.34) | HSD11B1HTTSMN1; SMN2MAPTRAB9A | |
| SCHEMBL29613248 | 0.80 | HTT (0.34) | HSD11B1HTTSMN1; SMN2MAPTRAB9A | |
| SCHEMBL23178526 | 0.78 | BCHE (0.36) | HTTSMN1; SMN2KDM4E | |
| SCHEMBL29613360 | 0.78 | BCHE (0.36) | HTTSMN1; SMN2KDM4E | |
| SCHEMBL24644734 | 0.78 | HTT (0.34) | HSD11B1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466913-B | Dihydro quinoline photochromic compounds | 光学转变有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-114466913-A | Dihydroquinoline photochromic compounds | 光学转变有限公司 | 2022-05-10 | — | — | CN | disclosed |