Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21354256 | 1.00 | RORC (0.49) | RORCKCNH2DHODH | |
| SCHEMBL19785799 | 1.00 | RORC (0.49) | RORCKCNH2DHODH | |
| SCHEMBL19785924 | 1.00 | RORC (0.49) | RORCKCNH2DHODH | |
| SCHEMBL29613294 | 1.00 | RORC (0.49) | RORCKCNH2DHODH | |
| SCHEMBL21354311 | 0.98 | RORC (0.51) | RORCKCNH2DHODH | |
| SCHEMBL21354308 | 0.98 | RORC (0.51) | RORCKCNH2DHODH | |
| SCHEMBL29613310 | 0.98 | RORC (0.51) | RORCKCNH2DHODH | |
| SCHEMBL21354310 | 0.98 | RORC (0.47) | RORCKCNH2 | |
| SCHEMBL19785809 | 0.98 | RORC (0.47) | RORCKCNH2 | |
| SCHEMBL29613379 | 0.98 | RORC (0.47) | RORCKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476653-B | Heteroaromatic modulators of retinoid-related orphan receptor gamma | 利奥制药有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-109476653-B | Heteroaromatic modulators of retinoid-related orphan receptor gamma | 利奥制药有限公司 | 2022-04-22 | — | — | CN | disclosed |