Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 17/20 | 0.84 |
| ▸ | CCNH | P51946 | 16/20 | 0.84 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.84 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.84 |
| ▸ | CDK1 | P06493 | 2/20 | 0.84 |
| ▸ | CDK2 | P24941 | 2/20 | 0.84 |
| ▸ | CDK9 | P50750 | 2/20 | 0.84 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.84 |
| ▸ | CDK13 | Q14004 | 2/20 | 0.84 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.84 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.84 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.84 |
| ▸ | CCNK | O75909 | 1/20 | 0.84 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.84 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.84 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.84 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.84 |
| ▸ | CDK8 | P49336 | 1/20 | 0.76 |
| ▸ | EGFR | P00533 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29129160 | 1.00 | CDK7 (0.84) | CDK7CCNHCDK5CDK5R1CDK1 | |
| SCHEMBL23682983 | 0.91 | CDK7 (1.00) | CDK7CCNHCDK5CDK5R1CDK1 | |
| SCHEMBL29434968 | 0.91 | CDK7 (1.00) | CDK7CCNHCDK5CDK5R1CDK1 | |
| SCHEMBL29355500 | 0.91 | CDK7 (1.00) | CDK7CCNHCDK5CDK5R1CDK1 | |
| SCHEMBL14979765 | 0.91 | CDK7 (1.00) | CDK7CCNHCDK5CDK5R1CDK1 | |
| SCHEMBL18229934 | 0.91 | CDK7 (1.00) | CDK7CCNHCDK5CDK5R1CDK1 | |
| SCHEMBL20204769 | 0.91 | CDK7 (0.81) | CDK7CCNHCDK5CDK5R1CDK1 | |
| Hydrochloric Acid SCHEMBL29867414 | 0.91 | CDK7 (0.99) | CDK7CCNHCDK5CDK5R1CDK1 | |
| SCHEMBL24510190 | 0.90 | CDK7 (0.90) | CDK7CCNHCDK5CDK5R1CDK1 | |
| SCHEMBL24510773 | 0.89 | CDK7 (0.87) | CDK7CCNHCDK5CDK5R1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4259133-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2023-10-18 | — | — | EP | disclosed |
| WO-2022126000-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2022-06-16 | — | — | WO | disclosed |