Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 15/20 | 1.00 |
| ▸ | CCNK | O75909 | 15/20 | 1.00 |
| ▸ | CDK9 | P50750 | 15/20 | 1.00 |
| ▸ | CDK12 | Q9NYV4 | 15/20 | 1.00 |
| ▸ | CCNE1 | P24864 | 14/20 | 1.00 |
| ▸ | CDK2 | P24941 | 14/20 | 1.00 |
| ▸ | CDK7 | P50613 | 13/20 | 1.00 |
| ▸ | CCNH | P51946 | 12/20 | 1.00 |
| ▸ | CRBN | Q96SW2 | 1/20 | 1.00 |
| ▸ | MNAT1 | P51948 | 11/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24839342 | 1.00 | CCNT1 (1.00) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL20190942 | 1.00 | CCNT1 (1.00) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL20190945 | 1.00 | CCNT1 (1.00) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL17150537 | 0.94 | CCNK (0.89) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25328316 | 0.94 | CCNK (0.89) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL29596542 | 0.94 | CCNK (0.89) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL30523927 | 0.94 | CCNK (0.89) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25329765 | 0.90 | CDK2 (0.83) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL17141346 | 0.89 | CDK2 (0.79) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24839797 | 0.88 | CCNT1 (1.00) | CCNT1CCNKCDK9CDK12CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480029-A | 2-Aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-08-13 | — | — | CN | disclosed |
| EP-4259133-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2023-10-18 | — | — | EP | disclosed |
| WO-2022126000-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2022-06-16 | — | — | WO | disclosed |