Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 18/20 | 0.89 |
| ▸ | CDK12 | Q9NYV4 | 18/20 | 0.89 |
| ▸ | CCNT1 | O60563 | 16/20 | 0.89 |
| ▸ | CDK9 | P50750 | 16/20 | 0.89 |
| ▸ | CDK7 | P50613 | 14/20 | 0.89 |
| ▸ | CCNE1 | P24864 | 14/20 | 0.89 |
| ▸ | CDK2 | P24941 | 14/20 | 0.89 |
| ▸ | CCNH | P51946 | 13/20 | 0.89 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.89 |
| ▸ | MNAT1 | P51948 | 12/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25328316 | 1.00 | CCNK (0.89) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL30523927 | 1.00 | CCNK (0.89) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL17150537 | 1.00 | CCNK (0.89) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL20190945 | 0.94 | CCNT1 (1.00) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL24839342 | 0.94 | CCNT1 (1.00) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL29613489 | 0.94 | CCNT1 (1.00) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL20190942 | 0.94 | CCNT1 (1.00) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL6039764 | 0.94 | CDK2 (0.78) | CCNKCDK12CCNT1CDK9CDK7 | |
| SCHEMBL29994490 | 0.94 | CDK2 (0.78) | CCNKCDK12CCNT1CDK9CDK7 | |
| Hydrochloric Acid SCHEMBL17141264 | 0.93 | CDK2 (0.76) | CCNKCDK12CCNT1CDK9CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114401955-A | Inhibitors of cyclin dependent kinases | 金耐特生物制药公司 | 2022-04-26 | — | — | CN | disclosed |