Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19785788 | 1.00 | RORC (0.34) | RORCKCNH2PTGDR2CCR1MGLL | |
| SCHEMBL21368553 | 0.91 | MAPT (0.37) | RORCKCNH2PTGDR2CCR1 | |
| SCHEMBL28278573 | 0.90 | — | — | |
| SCHEMBL19785969 | 0.89 | RORC (0.35) | RORCKCNH2PTGDR2CCR1MGLL | |
| SCHEMBL29613585 | 0.89 | RORC (0.35) | RORCKCNH2PTGDR2CCR1MGLL | |
| SCHEMBL21354294 | 0.88 | RORC (0.38) | RORCKCNH2PTGDR2MGLL | |
| SCHEMBL29613560 | 0.88 | PTGDR2 (0.41) | RORCPTGDR2CCR1 | |
| SCHEMBL19785976 | 0.88 | PTGDR2 (0.41) | RORCPTGDR2CCR1 | |
| SCHEMBL29613578 | 0.84 | RORC (0.47) | RORCKCNH2 | |
| SCHEMBL19785980 | 0.84 | RORC (0.47) | RORCKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476653-B | Heteroaromatic modulators of retinoid-related orphan receptor gamma | 利奥制药有限公司 | 2022-04-22 | — | — | CN | disclosed |