Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 15/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.53 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21354338 | 1.00 | RORC (0.53) | RORCKCNH2GRM1GAA | |
| SCHEMBL19785887 | 0.98 | RORC (0.51) | RORCKCNH2GRM1 | |
| SCHEMBL29613568 | 0.98 | RORC (0.51) | RORCKCNH2GRM1 | |
| SCHEMBL21354273 | 0.87 | RORC (0.40) | RORCKCNH2 | |
| SCHEMBL19785980 | 0.86 | RORC (0.47) | RORCKCNH2 | |
| SCHEMBL29613578 | 0.86 | RORC (0.47) | RORCKCNH2 | |
| SCHEMBL19785979 | 0.83 | SETD7 (0.36) | RORCKCNH2 | |
| SCHEMBL29613569 | 0.83 | SETD7 (0.36) | RORCKCNH2 | |
| SCHEMBL29613585 | 0.82 | RORC (0.35) | RORCKCNH2 | |
| SCHEMBL19785969 | 0.82 | RORC (0.35) | RORCKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476653-B | Heteroaromatic modulators of retinoid-related orphan receptor gamma | 利奥制药有限公司 | 2022-04-22 | — | — | CN | disclosed |