Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.51 |
| ▸ | AR | P10275 | 5/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29257436 | 1.00 | CRBN (0.51) | CRBNDDB1ARPRMT5WDR77 | |
| SCHEMBL23249925 | 0.95 | CRBN (0.49) | CRBNDDB1ARPRMT5WDR77 | |
| SCHEMBL29874161 | 0.95 | CRBN (0.49) | CRBNDDB1ARPRMT5WDR77 | |
| SCHEMBL22291262 | 0.93 | CRBN (0.55) | CRBNDDB1PRMT5WDR77ALK | |
| SCHEMBL31560072 | 0.93 | CRBN (0.55) | CRBNDDB1PRMT5WDR77ALK | |
| SCHEMBL22291558 | 0.92 | CRBN (0.49) | CRBNDDB1ARPRMT5WDR77 | |
| SCHEMBL30696651 | 0.91 | CRBN (0.48) | CRBNDDB1ARPRMT5WDR77 | |
| SCHEMBL30805384 | 0.88 | CRBN (0.51) | CRBNDDB1PRMT5WDR77ALK | |
| SCHEMBL31413428 | 0.88 | CRBN (0.53) | CRBNDDB1 | |
| SCHEMBL31413456 | 0.88 | CRBN (0.53) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240743-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Prelude Therapeutics, Incorporated (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099117-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | PRELUDE THERAPEUTICS INCORPORATED (US) | 2022-05-12 | — | — | WO | disclosed |