Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.49 |
| ▸ | AR | P10275 | 5/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | GRAMD1A | Q96CP6 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23249925 | 1.00 | CRBN (0.49) | CRBNDDB1ARPRMT5WDR77 | |
| SCHEMBL29257436 | 0.95 | CRBN (0.51) | CRBNDDB1ARPRMT5WDR77 | |
| SCHEMBL29614689 | 0.95 | CRBN (0.51) | CRBNDDB1ARPRMT5WDR77 | |
| SCHEMBL30718559 | 0.90 | CRBN (0.53) | CRBNDDB1GRAMD1A | |
| SCHEMBL30718824 | 0.90 | CRBN (0.53) | CRBNDDB1GRAMD1A | |
| SCHEMBL31413428 | 0.90 | CRBN (0.53) | CRBNDDB1GRAMD1A | |
| SCHEMBL31413456 | 0.90 | CRBN (0.53) | CRBNDDB1GRAMD1A | |
| SCHEMBL31560072 | 0.90 | CRBN (0.55) | CRBNDDB1PRMT5WDR77 | |
| SCHEMBL22291262 | 0.90 | CRBN (0.55) | CRBNDDB1PRMT5WDR77 | |
| SCHEMBL30696651 | 0.88 | CRBN (0.48) | CRBNDDB1ARPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045496-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | Arvinas Operations, Inc. (US) | 2022-08-24 | — | — | EP | disclosed |