SCHEMBL29614734

SCHEMBL29614734

CC(C)(C)c1cccc(C(C)(C)C)c1O.[Na]

nearest known ligand 0.94

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.94
GABRA1 P14867 2/20 0.70
GABRB2 P47870 2/20 0.70
ALDH1A1 P00352 5/20 0.56
TSHR P16473 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
ALOX12 P18054 1/20 0.55
CA1 P00915 2/20 0.52
SMN1; SMN2 Q16637 3/20 0.50
TYR P14679 2/20 0.50
POLB P06746 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
PTGS1 P23219 3/20 0.46
PTGS2 P35354 3/20 0.46
ALOX5 P09917 2/20 0.46
ALOX15 P16050 3/20 0.44
MAPT P10636 2/20 0.44
HPN P05981 1/20 0.44
SIRT5 Q9NXA8 1/20 0.44
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38598 0.97 CA2 (1.00) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL29978072 0.94 CA2 (0.94) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL30027561 0.94 CA2 (0.94) CA2GABRA1GABRB2ALDH1A1TSHR
Hydrochloric Acid SCHEMBL28473948 0.94 CA2 (0.94) CA2GABRA1GABRB2ALDH1A1TSHR
Hydrochloric Acid SCHEMBL7076174 0.94 CA2 (0.94) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL31622310 0.94 CA2 (0.94) CA2GABRA1GABRB2ALDH1A1TSHR
Methyl Alcohol SCHEMBL28909622 0.94 CA2 (0.94) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL28578522 0.94 CA2 (0.94) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL22444875 0.94 CA2 (0.94) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL28361779 0.94 CA2 (0.94) CA2GABRA1GABRB2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110862318-B Preparation method of tert-butyl substituted hydroxybenzoate 甘肃省化工研究院有限责任公司 2022-05-13 CN claimed
CN-116148381-A Method for detecting content of intermediate of hindered phenol light stabilizer 甘肃省化工研究院有限责任公司 2023-05-23 CN disclosed
CN-110862318-B Preparation method of tert-butyl substituted hydroxybenzoate 甘肃省化工研究院有限责任公司 2022-05-13 CN disclosed