Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.61 |
| ▸ | KIT | P10721 | 3/20 | 0.61 |
| ▸ | ABL1 | P00519 | 4/20 | 0.60 |
| ▸ | ABL2 | P42684 | 1/20 | 0.60 |
| ▸ | RET | P07949 | 6/20 | 0.58 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.57 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.57 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.54 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19307123 | 1.00 | CSF1R (0.61) | CSF1RKITABL1ABL2RET | |
| SCHEMBL29614832 | 0.87 | FGFR4 (0.57) | KITABL1ABL2RETSRC | |
| SCHEMBL19307128 | 0.87 | FGFR4 (0.57) | KITABL1ABL2RETSRC | |
| SCHEMBL24449142 | 0.86 | ABL1 (0.55) | ABL1ABL2RETSRCFGFR4 | |
| SCHEMBL19316725 | 0.85 | ABL1 (0.64) | KITABL1ABL2RETSRC | |
| SCHEMBL29614822 | 0.85 | ABL1 (0.58) | KITABL1ABL2RETSRC | |
| SCHEMBL19307146 | 0.85 | ABL1 (0.58) | KITABL1ABL2RETSRC | |
| SCHEMBL19316724 | 0.85 | CDK8 (0.56) | ABL1ABL2RETSRCFGFR4 | |
| SCHEMBL19322516 | 0.84 | SRC (0.58) | KITABL1ABL2RETSRC | |
| SCHEMBL24448254 | 0.83 | ABL1 (0.70) | CSF1RKITABL1ABL2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220160705-A1 | METHODS FOR CONTROLLING PROSTAGLANDIN-MEDIATED BIOLOGICAL PROCESSES | CORNELL UNIVERSITY | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220160705-A1 | METHODS FOR CONTROLLING PROSTAGLANDIN-MEDIATED BIOLOGICAL PROCESSES | PTGES, PTGS1, PTGES2 | CSF1R 4026/4885KIT 2155/4885ABL1 4516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.