Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24436419 | 1.00 | KRAS (0.54) | KRASSOS1 | |
| SCHEMBL22848276 | 0.90 | KRAS (0.51) | KRASSOS1 | |
| SCHEMBL28695435 | 0.85 | KRAS (0.53) | KRASSOS1 | |
| SCHEMBL31052998 | 0.85 | KRAS (0.46) | KRASSOS1 | |
| SCHEMBL28696808 | 0.83 | KRAS (0.41) | KRASSOS1 | |
| SCHEMBL22848275 | 0.81 | KRAS (0.42) | KRAS | |
| SCHEMBL29614787 | 0.81 | KRAS (0.42) | KRAS | |
| SCHEMBL31053011 | 0.79 | KRAS (0.50) | KRASSOS1 | |
| SCHEMBL29238703 | 0.79 | KRAS (0.50) | KRASSOS1 | |
| SCHEMBL22848330 | 0.79 | KRAS (0.41) | KRASSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008037-B | Heterocyclic compounds as KRAS G12C inhibitors | 广东新契生物医药科技有限公司 | 2024-06-21 | — | — | CN | disclosed |
| EP-3990448-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF KRAS G12C | Guangdong Newopp Biopharmaceuticals Co., Ltd. (CN) | 2022-05-04 | — | — | EP | disclosed |