Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24436419 | 0.79 | KRAS (0.54) | KRASSOS1 | |
| SCHEMBL29614930 | 0.79 | KRAS (0.54) | KRASSOS1 | |
| SCHEMBL22848276 | 0.70 | KRAS (0.51) | KRASSOS1 | |
| SCHEMBL22848275 | 0.69 | KRAS (0.42) | KRAS | |
| SCHEMBL29614787 | 0.69 | KRAS (0.42) | KRAS | |
| SCHEMBL20806992 | 0.68 | KRAS (0.66) | KRAS | |
| SCHEMBL20806966 | 0.68 | KRAS (0.66) | KRAS | |
| SCHEMBL22848331 | 0.68 | KRAS (0.36) | KRAS | |
| SCHEMBL20805595 | 0.67 | KRAS (0.67) | KRAS | |
| SCHEMBL31052998 | 0.67 | KRAS (0.46) | KRASSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020259513-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF KRAS G12C | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2020-12-30 | — | — | WO | disclosed |