SCHEMBL2961496

SCHEMBL2961496

C=Cc1ccccc1C(C)N(CCC)CCC

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 5/20 0.36
KCNH2 Q12809 1/20 0.36
CYP2D6 P10635 1/20 0.34
KCNE1 P15382 1/20 0.34
ALDH1A1 P00352 1/20 0.33
KCNJ5 P48544 1/20 0.31
KCNJ3 P48549 1/20 0.31
SCN5A Q14524 1/20 0.31
KCND3 Q9UK17 1/20 0.31
TSHR P16473 1/20 0.31
HSF1 Q00613 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3449204 0.90 TDP1 (0.32) ALDH1A1
SCHEMBL2953628 0.88 KCNH2 (0.35) KCNH2
SCHEMBL9779045 0.88 KCNH2 (0.35) KCNH2
SCHEMBL3448138 0.88 KCNH2 (0.35) KCNH2
SCHEMBL9779370 0.88 KCNH2 (0.35) KCNH2
SCHEMBL1673075 0.86 ALDH1A1 (0.35) KCNH2CYP2D6ALDH1A1TSHR
SCHEMBL6469999 0.81 ALDH1A1 (0.34) CYP2D6ALDH1A1TSHR
SCHEMBL10628486 0.78 KCNA5 (0.33) KCNA5KCNH2CYP2D6KCNE1ALDH1A1
SCHEMBL11811176 0.77 TSHR (0.37) ALDH1A1TSHR
SCHEMBL3447816 0.77 ALDH1A1 (0.39) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6111045-A YIELDS A VULCANIZED RUBBER SHOWING IMPROVEMENTS IN HEAT BUILD-UP, TENSILE STRENGTH, ABRASION RESISTANCE AND PROCESSABILITY NIPPON ZEON CO. LTD. (JP) 2000-08-29 US claimed
US-7790799-B2 Reinforced silica/elastomer composite THE GOODYEAR TIRE & RUBBER COMPANY (US) 2010-09-07 US disclosed
US-7767111-B2 Surface conditioner and method of surface conditioning NIPPON PAINT CO., LTD. (JP) 2010-08-03 US disclosed
EP-1380604-B1 OIL-EXTENDED RUBBER AND RUBBER COMPOSITION ZEON CORP (JP) 2008-01-02 EP disclosed
US-20070272339-A1 Reinforced silica/elastomer composite THE GOODYEAR TIRE & RUBBER COMPANY (US) 2007-11-29 US disclosed
US-7276550-B2 Reinforced silica/elastomer composite THE GOODYEAR TIRE & RUBBER COMPANY (US) 2007-10-02 US disclosed
EP-1215226-B1 Diene-based rubber/inorganic compound complexes, methods for producing the same and rubber compositions containing the same JSR CORP (JP) 2006-06-07 EP disclosed
US-7055566-B2 Light weight rubber composition containing clay THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-06-06 US disclosed
US-7045578-B2 Oil extended rubber and rubber composition ZEON CORPORATION (JP) 2006-05-16 US disclosed
US-20050187326-A1 Surface conditioner and method of surface conditioning NIPPON PAINT HOLDINGS CO., LTD. (JP) 2005-08-25 US disclosed
US-6075092-A DIENE RUBBER AND A SPECIFIED ETHYLENE OXIDE-PROPYLENE OXIDE-UNSATURATED OXIDE TERPOLYMER HAVING GIVEN MOONEY VISCOSITY; EXCELLENT HEAT BUILD-UP RESISTANCE, TENSILE STRENGTH AND PROCESSABILITY NIPPON ZEON CO., LTD. (JP) 2000-06-13 US disclosed
US-6013737-A HAVING IMPROVED TENSILE MODULUS AND IMPROVED ABRASION RESISTANCE, COMPRISING AN AMINO GROUP-CONTAINING DIENE RUBBER OF GIVEN MOONEY VISCOSITY, AND SILICA HAVING SPECIFIC SURFACE AREA, A VULCANIZER AND VULCANIZATION ACCELERATOR NIPPON ZEON CO., LTD. (JP) 2000-01-11 US disclosed
EP-0894825-A1 DIENE POLYMER COMPOSITION, PROCESS FOR THE PREPARATION OF THE SAME, AND RUBBER COMPOSITION CONTAINING THE SAME NIPPON ZEON CO., LTD. (JP) 1999-02-03 EP disclosed
EP-0894824-A1 RUBBER COMPOSITION NIPPON ZEON CO., LTD. (JP) 1999-02-03 EP disclosed
EP-0882738-A1 DIENE RUBBER, PROCESS FOR PRODUCING THE RUBBER AND RUBBER COMPOSITION CONTAINING THE SAME NIPPON ZEON CO., LTD. (JP) 1998-12-09 EP disclosed
EP-0864606-A1 RUBBER COMPOSITION NIPPON ZEON CO., LTD. (JP) 1998-09-16 EP disclosed
EP-0849321-A1 DIENE RUBBER COMPOSITION NIPPON ZEON CO., LTD. (JP) 1998-06-24 EP disclosed
EP-0819731-A1 DIENE RUBBER COMPOSITION NIPPON ZEON CO., LTD. (JP) 1998-01-21 EP disclosed
US-5015551-A Resin particles dispersed in a dielectric nonaqueous solvent for making printing plates or sheets FUJI PHOTO FILM CO., LTD. (JP) 1991-05-14 US disclosed
US-4473630-A Liquid developer comprising aminoalkyl styrene polymer for electrostatic images FUJI PHOTO FILM CO., LTD. (JP) 1984-09-25 US disclosed