Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210689 | 0.88 | POLB (0.44) | POLBALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL16515849 | 0.86 | CA1 (0.45) | POLBALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL12377557 | 0.82 | LMNA (0.45) | POLBALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL2468887 | 0.81 | POLB (0.48) | POLBALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL526630 | 0.79 | IDO1 (0.56) | POLBALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL29291851 | 0.77 | HMGB1 (0.46) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL7206760 | 0.76 | IDO1 (0.53) | POLBALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL888293 | 0.76 | PADI4 (0.55) | POLBALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL30503415 | 0.76 | PADI4 (0.55) | POLBALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL29648165 | 0.76 | IDO1 (0.53) | POLBALDH1A1KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292503-B | Preparation method of 2-bromo-3-aminonaphthoquinone compound | 台州市第一人民医院 | 2022-05-13 | — | — | CN | disclosed |