⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3754153 | 1.00 | — | — | |
| SCHEMBL167008 | 1.00 | — | — | |
| Phosphine SCHEMBL28305182 | 0.97 | HSD17B10 (0.36) | — | |
| Thiophene SCHEMBL14351352 | 0.89 | PDPK1 (0.33) | — | |
| Formamide SCHEMBL28266187 | 0.87 | HSD17B10 (0.34) | — | |
| SCHEMBL27861155 | 0.83 | NPC1 (0.30) | — | |
| Carbazole SCHEMBL27899203 | 0.79 | ALDH1A1 (0.48) | — | |
| Thiophene SCHEMBL27831515 | 0.78 | — | — | |
| SCHEMBL29683812 | 0.77 | — | — | |
| SCHEMBL17865293 | 0.71 | NTRK1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111408-A1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY AND HUNTINGTON'S DISEASE | BIOGEN MA INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| CN-114585609-B | 2H-indazole derivatives and their use in the treatment of diseases | 比奥根MA公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-114245796-B | Imidazo [1,2-a ] pyridinyl derivatives and their use in the treatment of diseases | 比奥根MA公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-117940414-A | Compounds for targeting IRAK4 protein degradation | 渤健马萨诸塞州股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-110740996-B | Covalent small molecule DCN1 inhibitors and methods of treatment using the same | 密执安大学评议会 | 2024-01-09 | — | — | CN | disclosed |
| CN-116903634-A | Preparation method of 6-phenylthieno [2,3-b ] pyrazine | 上海美迪西生物医药股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-114585609-A | 2H-indazole derivatives and their use in the treatment of diseases | 比奥根MA公司 | 2022-06-03 | — | — | CN | disclosed |
| EP-3990432-A1 | 2H-INDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | Biogen MA Inc. (US) | 2022-05-04 | — | — | EP | disclosed |
| CN-114245796-A | Imidazo [1,2-a ] pyridinyl derivatives and their use in the treatment of disease | 比奥根MA公司 | 2022-03-25 | — | — | CN | disclosed |