Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.52 |
| ▸ | MC5R | P33032 | 1/20 | 0.52 |
| ▸ | MC3R | P41968 | 1/20 | 0.52 |
| ▸ | MC1R | Q01726 | 1/20 | 0.52 |
| ▸ | TFPI | P10646 | 4/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KDM5A | P29375 | 1/20 | 0.51 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 7/20 | 0.51 |
| ▸ | NPY4R | P50391 | 7/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.51 |
| ▸ | NPY1R | P25929 | 5/20 | 0.51 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.50 |
| ▸ | RAMP3 | O60896 | 3/20 | 0.50 |
| ▸ | CALCR | P30988 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31326910 | 1.00 | MC4R (0.52) | MC4RMC5RMC3RMC1RTFPI | |
| SCHEMBL30176438 | 0.90 | NPY2R (0.59) | TFPINPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL31070020 | 0.88 | NPY2R (0.54) | TFPIKDM1AMAOBKDM5AKDM1B | |
| SCHEMBL30906350 | 0.88 | NPY2R (0.59) | TFPIKDM1AMAOBKDM5AKDM1B | |
| SCHEMBL30844327 | 0.88 | RAMP3 (0.55) | TFPINPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30601492 | 0.87 | APLNR (0.51) | KDM1AMAOBKDM5AKDM1BC5AR1 | |
| SCHEMBL30906458 | 0.87 | NPY2R (0.57) | KDM1AMAOBKDM5AKDM1BNPY2R | |
| SCHEMBL30906413 | 0.87 | NPY2R (0.57) | KDM1AMAOBKDM5AKDM1BNPY2R | |
| SCHEMBL30906538 | 0.87 | RAMP3 (0.55) | NPY2RNPY4RNPY5RNPY1RRAMP3 | |
| SCHEMBL29638084 | 0.87 | CALCR (0.48) | MC4RMC5RMC3RMC1RTFPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119424371-A | ERK2-siRNA nano delivery system, preparation and application thereof in inhibiting vascular intimal hyperplasia | 福建医科大学附属第一医院 | 2025-02-14 | — | — | CN | claimed |
| CN-114469891-B | Micromolecule drug/therapeutic gene combined delivery system with enzyme sensitive shell and preparation method and application thereof | 中山大学附属第一医院 | 2023-01-24 | — | — | CN | claimed |
| US-20250223319-A1 | IMPROVED CHIMERIC POLYPEPTIDES AND USES THEREOF | THE UNIVERSITY OF QUEENSLAND (AU) | 2025-07-10 | — | — | US | disclosed |
| CN-119424371-A | ERK2-siRNA nano delivery system, preparation and application thereof in inhibiting vascular intimal hyperplasia | 福建医科大学附属第一医院 | 2025-02-14 | — | — | CN | disclosed |
| EP-4499668-A1 | IMPROVED CHIMERIC POLYPEPTIDES AND USES THEREOF | The University of Queensland (AU) | 2025-02-05 | — | — | EP | disclosed |
| CN-119318716-A | Folic acid-polylactic acid double-layer vesicle delivery system for targeting MDSC cells in focus, and preparation method and application thereof | 中山大学附属第一医院 | 2025-01-17 | — | — | CN | disclosed |
| WO-2023187743-A1 | IMPROVED CHIMERIC POLYPEPTIDES AND USES THEREOF | THE UNIVERSITY OF QUEENSLAND (AU) | 2023-10-05 | — | — | WO | disclosed |
| CN-114469891-B | Micromolecule drug/therapeutic gene combined delivery system with enzyme sensitive shell and preparation method and application thereof | 中山大学附属第一医院 | 2023-01-24 | — | — | CN | disclosed |
| CN-114469891-A | Micromolecule drug/therapeutic gene combined delivery system with enzyme sensitive shell and preparation method and application thereof | 中山大学附属第一医院 | 2022-05-13 | — | — | CN | disclosed |