SCHEMBL29616475

SCHEMBL29616475

CC(C)(C)OC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.54
EPHX2 P34913 1/20 0.49
PTPRC P08575 2/20 0.45
CASP3 P42574 1/20 0.44
OPRD1 P41143 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19931854 1.00 KMT2A (0.54) KMT2AEPHX2PTPRCCASP3OPRD1
SCHEMBL26352259 0.95 KMT2A (0.51) KMT2AEPHX2PTPRCCASP3OPRD1
SCHEMBL27072523 0.95 KMT2A (0.51) KMT2AEPHX2PTPRCCASP3OPRD1
SCHEMBL30095461 0.91 KMT2A (0.54) KMT2AEPHX2PTPRCCASP3
SCHEMBL469368 0.91 KMT2A (0.54) KMT2AEPHX2PTPRCCASP3
Hydrochloric Acid SCHEMBL455447 0.90 KMT2A (0.53) KMT2AEPHX2PTPRCCASP3OPRD1
SCHEMBL18982241 0.90 KMT2A (0.49) KMT2AEPHX2CASP3
SCHEMBL18411293 0.89 KMT2A (0.55) KMT2AEPHX2PTPRCCASP3
SCHEMBL26172640 0.89 KMT2A (0.60) KMT2AEPHX2CASP3
SCHEMBL12391727 0.88 KMT2A (0.57) KMT2AEPHX2CASP3OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12122815-B2 GIP receptor agonist peptide compounds and uses thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-10-22 US disclosed
US-20220135638-A1 GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135638-A1 GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF GIPR, GLP1R, VIPR1 KMT2A 2759/4885EPHX2 4666/4885PTPRC 2023/4885
US-12122815-B2 GIP receptor agonist peptide compounds and uses thereof GIPR, GLP1R, GPR119 KMT2A 2421/4885EPHX2 4698/4885PTPRC 2496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.