Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.51 |
| ▸ | NPC1 | O15118 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15174879 | 1.00 | RAB9A (0.55) | RAB9AMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL15174964 | 0.92 | KDM4E (0.49) | RAB9AMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL15174771 | 0.91 | RAB9A (0.55) | RAB9AMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL15605666 | 0.91 | RAB9A (0.57) | RAB9AMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL15183155 | 0.90 | RAB9A (0.57) | RAB9AMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL22862013 | 0.85 | KDM4E (0.57) | RAB9AMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL15183006 | 0.82 | MEN1 (0.53) | RAB9AMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL24918857 | 0.81 | KDM4E (0.55) | RAB9AMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL15174269 | 0.81 | KDM4E (0.51) | RAB9AMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL24919874 | 0.81 | POLB (0.57) | RAB9AMEN1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3993818-A2 | CD38-BINDING AGENTS AND USES THEREOF | Kleo Pharmaceuticals, Inc. (US) | 2022-05-11 | — | — | EP | disclosed |
| CN-114401732-A | CD38 binding agents and uses thereof | 克莱奥药品有限公司 | 2022-04-26 | — | — | CN | disclosed |