Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.57 |
| ▸ | KDM4A | O75164 | 4/20 | 0.54 |
| ▸ | KDM4B | O94953 | 4/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | KDM5C | P41229 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15173226 | 1.00 | ADORA3 (0.57) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL23417815 | 0.92 | ADORA3 (0.56) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL23417740 | 0.91 | ADORA3 (0.56) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL15173407 | 0.90 | KDM4A (0.54) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL23418017 | 0.89 | ADORA3 (0.55) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL26421517 | 0.89 | ADORA3 (0.55) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL26421519 | 0.87 | ADORA3 (0.52) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL15182791 | 0.87 | MAPT (0.49) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL23417908 | 0.86 | ADORA3 (0.51) | ADORA3KDM4AKDM4BKDM5BKDM4E | |
| SCHEMBL23417847 | 0.86 | ADORA3 (0.66) | ADORA3KDM4AKDM4BKDM5BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3993818-A2 | CD38-BINDING AGENTS AND USES THEREOF | Kleo Pharmaceuticals, Inc. (US) | 2022-05-11 | — | — | EP | disclosed |
| CN-114401732-A | CD38 binding agents and uses thereof | 克莱奥药品有限公司 | 2022-04-26 | — | — | CN | disclosed |